About Me

Introduction

Hi, I'm Abby! I'm currently a graduate student working at Washington University in St. Louis planning to defend my thesis in the spring of 2024. My work with Dave Pagliarini's group focuses on the structure and function of mitochondrial and peroxisomal enzymes involved in lipid metabolism.


During my graduate career, I've learned how to teach and communicate science at the intersection of biology and health, especially as it relates to the biochemical underpinnings of rare disease. I've brought rare disease education to the classroom, creating a seminar curriculum for UW-Madison’s biochemistry capstone course centering on molecular mechanisms of mitochondrial disorders. Through my work with rare-focused patient organizations such as the United Mitochondrial Disease Foundation, I've seen firsthand how much of a difference it makes for individuals and families to learn about and get involved in research efforts surrounding their rare conditions. As I look forward to my next career chapter, I'm eagerly seeking an opportunity that will give me both a strong career foundation and the chance to make an impact in the lives of rare disease patients and their loved ones.

Experience

University of Wisconsin-Madison
Integrated Program in Biochemistry PhD (Spring 2024*)

As a current graduate student, I am involved in many research, teaching, science outreach and professional development activities, both in the rigorous training environment of UW-Madison and in my new position with the recently relocated Pagliarini lab at Washington University in St. Louis. My research centers on coenzyme Q biosynthesis and atypical fatty acid catabolism, with a focus on the protein structure and function of redox-active enzymes in these pathways. I am a Biotechnology Training Program trainee through the NIH as well as an NSF graduate research fellow. 

Biochemistry Capstone Instructor (Fall 2018 - Spring 2020) 

As a part of my curriculum in IPiB, I served as a teaching assistant (TA) for two semesters of the undergraduate biochemistry capstone laboratory course. I have also engaged in further teaching opportunities, such as designing and teaching a senior capstone seminar for undergraduate biochemistry majors at UW-Madison. My activities in this role include designing the a curriculum about the molecular mechanisms of mitochondrial disease and dysfunction, giving in-class and in-lab lectures, and providing one-on-one course and career guidance to students.

Science Outreach

At UW, I volunteered for many outreach events, including Saturday Science at the Wisconsin Institutes for Discovery and elementary school science fairs in underserved communities around Madison. I also perform teen and adult outreach through the United Mitochondrial Disease Foundation, a group that advocates for individuals with rare mitochondrial diseases. Activities I've led in this capacity include participating in fundraiser walks and hosting patients and families for outreach events at the Pagliarini lab. 

Rare Disease Advocacy

After the Pagliarini lab's move to WashU, I found new opportunities to focus on my interest in rare disease. I have engaged in some outreach and shadowing activities with the Undiagnosed Diseases Network (UDN) to aid their work with rare disease patients who are still searching for their genetic diagnosis. In addition, I have served as the 5K race chair for UMDF's St. Louis Energy for Life Walk and 5K for 2022 and 2023. During this time, I decided to focus on rare diseases in my future career; I have taken WUSTL's CITI GCP training and the NIH's course on the principles of clinical research to learn more about clinical research practices and am excited for my future career in this area!  

Auburn University
BS Biochemistry, BS Cellular and Molecular Biology (2017)

During my time at Auburn University, I participated in the Auburn University Honors College, completing an honors thesis and earning the distinction of University Honors Scholar. I was also involved with many on-campus organizations, including Residence Life as a Resident Assistant and as Vice President of the American Chemical Society campus chapter. I graduated Summa Cum Laude in 2017 with a BS in Biochemistry and a BS in Microbial, Cellular and Molecular Biology. 

Undergraduate Research

My research projects with Dr. Holly Ellis's group in the Department of Chemistry and Biochemistry focused on mechanisms of sulfur metabolism in bacterial systems.

Undergraduate Teaching Experiences

I was the primary student instructor for multiple Chemistry I, Biochemistry I and Biochemistry II lab sections over the course of six consecutive semesters. I provided instruction and demonstrated techniques for students, answered questions and provided guidance during the lab session, and engaged with students outside of regular class times through office hours and one-on-one meetings. 

Syracuse University
NSF Research Experience for Undergraduates (REU) Summer Fellow

My summer research experience with Dr. Ivan Korendovych's group focused on the synthesis and in vitro characterization of catalytic peptides.